Ebola Pseudoviruses

Easy and Ready-to-Use Pseudoviruses Advancing Influenza Research

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Our Ebola Pseudovirus Catalog

Check our Ebola pseudovirus library. Our 3rd-generation lentiviral vector-based pseudoviruses expose the glycoprotein of Ebola virus. If you can not find your pseudovirus of interest, our custom production service could support you. Don’t hesitate to reach out to learn more.

Ebola Zaire Pseudovirus

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Ebola Sudan Pseudovirus

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Bundibugyo Ebola Pseudovirus

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Advantages

Our rigorously validated pseudoviruses are available in multiple formats and concentrations, offering flexibility to match your experimental design and enhance the consistency of your results.

Support High-Throughput Screening

Various sizes available: 100 µL, 1 mL, 5 mL, 10 mL or more

Consistent results

Batch-to-batch quality and functional validation (infection, neutralization, and stability)

Enable Specific Detection

Expression of hemagglutinin as the sole surface antigen

Sensitive and Easy Detection

Achieve a 10³ RLU signal-to-background ratio with just 1 µL

Enhanced Safety

Use of a 3rd-generation lentivirus system for BSL-2 compatibility

Standard Neutralizing Antibody Available

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Ebola Pseudovirus

Ebola Pseudoviruses represent a robust and secure alternative to handling live Ebola virus in neutralization or infectivity assays. These replication-deficient viral particles are engineered to display the Ebola glycoprotein (GP), closely mimicking the native virus’s surface architecture, yet can be safely manipulated in BSL-2 environments, even when simulating highly virulent strains.

Because they are genetically stable, they eliminate variability linked to viral drift and reduce biosafety concerns. Each pseudovirus carries an integrated reporter gene (e.g., luciferase or GFP), allowing for fast, reliable quantification using standard lab instrumentation.

By removing the need for live virus culture, high-containment labs, and specialized training, Ebola pseudoviruses streamline experimental workflows and accelerate data generation, making them ideal for vaccine development, antibody screening, and therapeutic evaluation.

Applications

Pseudoviruses provide a safe and versatile platform for Ebola virus research and the development of therapeutic countermeasures. Ebola pseudoviruses have several important applications in research and development, including:

Vaccine Development

They are used to test the efficacy of new vaccines and antiviral drugs by evaluating their ability to induce neutralizing immune responses without the need for live pathogenic viruses.

Immune profiling

Assessment of immune persistence through the detection of neutralizing antibodies following vaccination or infection

Neutralizing Antibody Screening

Pseudoviruses enable rapid and safe screening of neutralizing antibodies targeting specific epitopes of the Ebola virus.

Antiviral Resistance Studies

They help study viral mutations and evaluate how these mutations affect sensitivity to antiviral treatments.

Fundamental Research on Viral Entry

Pseudoviruses are used to understand the mechanisms of viral entry into host cells, which is crucial for developing new therapies targeting these processes.

Treatment Efficacy Testing

They allow for the quick assessment of new antiviral agents’ effectiveness in controlled environments without the risks associated with highly pathogenic viruses.

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Documentations

Pseudoviruses CoA

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